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Senior Citizens & Sex

Senior Men have High Rate of Return to Sexual Function When Prostate Cancer Treated with Cryoablation

This minimally-invasive therapy and post-treatment rehab are keys to regaining potency

March 15, 2007 – Cryoablation - non-surgical freezing and destroying of cancerous tumors - is not only an effective primary treatment for localized prostate cancer but post-treatment sexual function can be rapidly and substantially increased if accompanied by a penile rehabilitation regimen, according to a study of 416 patients with an average age of 69.4 years.

 

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Endocare, Inc., manufacturers of the Cryocare System used in the study, said today that in this study, published in the February edition of the journal Urology, the patients chose cryoablation after being offered several other options including radical prostatectomy and radiation therapy.

The study, led by David S. Ellis, M.D., was conducted at United States Medical Development Hospital and Arlington Memorial Hospital, both in Arlington, Texas, and Baylor University Medical Center in Dallas. The mean patient age was 69.4 years and mean follow-up of the entire patient group was 20.4 months.

All the patients who were potent before the treatment were strongly encouraged to begin the penile rehabilitation regimen six weeks after the cryoablation therapy.

Dr. Ellis noted that the study directly links potency rates with a rehabilitation regimen after the cryoablation therapy. A total of 29.1 percent of the patients who were potent before cryoablation and underwent penile rehabilitation after the treatment regained potency in one year and 51.3 percent were potent four years later.

"This study demonstrated a substantially greater return to potency than in any series published to date," Dr. Ellis said. "We believe the reason for this rapid and high rate of return to sexual function was threefold: First, cryoablation is a minimally invasive therapy; second, the patients were told that there was a good chance that they would regain potency, which created a hopeful atmosphere; and finally, the regular rehabilitation program after cryoablation therapy effectively expedited the return to erectile function."

Dr. Ellis also noted that studies of men who have undergone focal cryoablation, a procedure in which only the diseased portion of the prostate is frozen, demonstrated post-treatment potency rates between 78 and 85 percent.

All the patients were treated with an Endocare Cryocare System, which non-surgically freezes and destroys the cancerous tumors in the prostate gland.

"It is important for patients to understand that the treatment of prostate cancer, particularly when they choose a minimally invasive therapy such as cryoablation, does not necessarily mean the end of their sexual potency, even when the entire gland is aggressively treated," said Endocare President, Chairman and CEO Craig T. Davenport. "This study demonstrates that cryoablation will effectively destroy the cancer in the prostate but also, if patients take charge of their post-treatment therapy and take on a rehabilitation regimen, there is a good chance that they may regain potency."

Studies Presented Last Year

Last November, Endocare reported there were 18 studies and papers demonstrating the effectiveness of cryoablation for treating prostate cancer and certain other types of cancer presented at the 92nd Scientific Assembly and Annual Meeting of the Radiological Society of North America.

The presentations included data from a 55-patient study on specially targeted cryoablation, also called focal cryoablation or the “male lumpectomy,” showing that in certain cases prostate cancer can be destroyed while carefully preserving a patient’s potency and continence, as well as a 20-patient study performed at the Mayo Clinic focusing on the use of cryoablation to relieve debilitating pain caused by metastatic tumors in bones.

All of the studies, Endocare reported, involved the non-surgical freezing and destroying of the cancerous tumors using an Endocare Cryocare System, which "has been shown to be a less invasive treatment option with the potential in many cases for less morbidity, faster recovery and fewer complications than standard surgical treatment options."

Cryoablation is effective in treating cancer patients' pain

A study, which appeared in the March 2005 issue of the American Journal of Roentgenology, found that cryoablation relieved the pain of four patients who had very advanced disease. The patients had various types of cancer that had spread to areas outside the abdomen organs, said Damian E. Dupuy, MD, professor of diagnostic imaging at Brown Medical School in Providence, RI. These patients were not candidates for surgery because the tumors were too close to critical structures or the patient had multi-focal disease. In addition, chemotherapy or radiation therapy had not been successful in controlling these areas of symptomatic disease.

About Endocare

Endocare, Inc. (www.endocare.com) says it is an innovative medical device company focused on the development of minimally invasive technologies for tissue and tumor ablation. Endocare has initially concentrated on developing technologies for the treatment of prostate cancer and believes that its proprietary technologies have broad applications across a number of markets, including the ablation of tumors in the kidney, lung and liver.

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