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Seniors Will Appreciate Study Finding Coffee Drinkers Less Likely to Get Alzheimer’s in Old Age

Drinking 3-5 cups per day shows best results – lowers Alzheimer’s risk by 65%

Jan. 28, 2009 – A survey several years ago found that most senior citizens would give up sex before they would their morning coffee. So, seniors, always pleased to hear good news about their favorite drink, will appreciate a new research report indicating people who consumed coffee at middle-age had lower risk for dementia and Alzheimer’s disease later in life, compared to those who drank little or no java.

This conclusion is made in a Finnish Cardiovascular Risk Factors, Aging and Dementia (CAIDE) Study published in the January 2009 issue of the Journal of Alzheimer's Disease.

 

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"We aimed to study the association between coffee and tea consumption at midlife and dementia/AD risk in late-life, because the long-term impact of caffeine on the central nervous system was still unknown, and as the pathologic processes leading to Alzheimer's disease may start decades before the clinical manifestation of the disease," says lead researcher, associate professor Miia Kivipelto, from the University of Kuopio, Finland and Karolinska Institutet, Stockholm, Sweden.

The study was conducted at the University of Kuopio in collaboration with Karolinska Institutet and the National Public Health Institute, Helsinki, Finland.

Participants included the survivors of population-based groups previously surveyed in the North Karelia Project and the FINMONICA study in 1972, 1977, 1982 or 1987 (midlife visit).

After an average follow-up of 21 years, 1409 individuals, (71%) aged 65 to 79, completed the re-examination in 1998. A total of 61 cases were identified as demented and 48 of these with AD.

At the midlife examination, the consumption of coffee and tea was assessed with a previously validated semi-quantitative food-frequency questionnaire.

Coffee drinking was categorized into three groups:
  ●  0-2 cups (low),
  ●  3-5 cups (moderate) and
  ●  >5 cups (high) per day.

Further, the question concerning tea consumption was divided into those not drinking tea and those drinking at least a cup of tea per day.

The study found that coffee drinkers at midlife had lower risk for dementia and AD later in life compared to those drinking no or only little coffee.

The lowest risk (65% decreased) was found among moderate coffee drinkers (drinking 3-5 cups of coffee/day). Adjustments for various confounders did not change the results.

Tea drinking was relatively uncommon and was not associated with dementia or AD.

"Given the large amount of coffee consumption globally, the results might have important implications for the prevention of or delaying the onset of dementia/AD,” says Kivipelto.

“The finding needs to be confirmed by other studies, but it opens the possibility that dietary interventions could modify the risk of dementia/AD. Also, identification of mechanisms of how coffee exerts its protection against dementia/AD might help in the development of new therapies for these diseases."

Background Information

Karolinska Institutet is one of the leading medical universities in Europe. Through research, education and information, Karolinska Institutet contributes to improving human health. Each year, the Nobel Assembly at Karolinska Institutet awards the Nobel Prize in Physiology or Medicine. For more information, visit ki.se

 

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