- Senior Citizens News & Information on Web Daily

   FRONT PAGE Aging  Health & Medicine  Mental Health-Alzheimer's  Fitness & Exercise  Nutrition & Vitamin  Medicare & Medicaid

   Social Security  Politics  Senior Statistics  Sex & Seniors  Senior Alerts  Features  Retirement Choices  Elder Care        Search


Health and Medicine for Seniors

3D Mammography Offers New Hope for Women: Finds More Invasive Cancers, Reduces Call-Backs

Largest study to date tested nearly half million women; could lead to changes in standards of care

Emily F. Conant, M.D., Penn Medicine examines 3D mammography. Study finds it detects more invasive cancers and reduces call-back rates - published in JAMA.

June 25, 2014 - Researchers from Penn Medicine and other institutions have found that 3D mammography - known as digital breast tomosynthesis will find significantly more invasive, or potentially lethal, cancers than a traditional mammogram alone and reduced call-backs for additional imaging. The study is reported today in the Journal of the American Medical Association (JAMA).

This is the largest study reported to date - with nearly a half a million women - measuring the effectiveness of the technology, and could potentially lead to a change in the standard of care for breast screening.

"It's the most exciting improvement to mammography that I have seen in my career, even more important for women than the conversion from film-screen mammography to digital mammography," said senior author Emily F. Conant, MD, chief of Breast Imaging the department of Radiology at the Perelman School of Medicine at the University of Pennsylvania. "3D mammography finds more clinically significant breast cancers earlier, which is the key so that women have more treatment options and ultimately better health outcomes."

In the retrospective study, the researchers looked at 281,187 digital mammography examinations and 173,663 examinations with both tomosynthesis and digital mammography between 2010 and 2012. The data set included women from a wide range of breast cancer screening programs that were both geographically diverse and included academic and community practices, 13 in total.


Related Archive Stories


Senior Women with Diabetes Less Likely to Have Mammogram Despite Higher Risk

Researchers find low socioeconomic status an additional obstacle to preventive care in already disadvantaged population

April 14, 2014


Read the latest news
> Health & Medicine
Today's Headlines


Researchers found 41 percent more invasive cancers when women were screened with tomosynthesis plus digital compared to digital mammography alone. The use of tomosynthesis also reduced the number of women called back for additional testing by 15 percent.

Conventional digital mammography is the most widely-used screening modality for breast cancer, but may yield suspicious findings that turn out not to be cancer, known as false-positives. Such findings are associated with a higher recall rate, or the rate at which women are called back for additional imaging or biopsy that may be deemed unnecessary.

Tomosynthesis, however, allows for 3-D reconstruction of the breast tissue, giving radiologists a clearer view of the overlapping slices of breast tissue. And though a relatively new technology, it has shown promise at reducing recall rates in all groups of patients, including younger women and those with dense breast tissue, and better detection rates in smaller studies. In 2011, tomosynthesis was approved by the U.S. Food and Drug Administration to be used in combination with standard digital mammography for breast cancer screening.

3D mammography is the only method used for breast cancer imaging that has demonstrated this combined benefit, the authors report. While 3D mammography found more invasive cancers, detection of in situ cancers (non-invasive cancers) was similar to a traditional mammography.

Since October 2011, all screening mammograms at Penn Medicine's Perelman Center for Advanced Center now include tomosynthesis according to Dr. Conant.

"The coming years will be very exciting, as we see further improvements in this innovative technology," said Conant. "This new technology will certainly change the way we screen women."

The study also included lead author Sarah M. Friedewald, MD, of the Caldwell Breast Center at Advocate Lutheran General Hospital; Elizabeth Rafferty, MD; Stephen L. Rose, MD; Melissa Durand, MD; Donna Plecha, MD; Julianne Greenberg, MD; Mary K. Hayes, MD; Debra S. Copit, MD; Kara Carlson, MD; Thomas Cink, MD; Lora Barke, MD; Linda Greer, MD; and David Miller, MS.



> Medical Malpractice,

> Nursing Home Abuse,

> Personal Injury

Our Experienced Lawyers Can Help

Beth Janicek, Board Certified Personal Injury Attorney"We win because we care, we prepare and we have no fear," Beth Janicek, board certified personal injury attorney


Free Consultation on your case.

Call Now Toll Free


or Send Email

More at our Website



Search for more about this topic on

Google Web

Keep up with the latest news for senior citizens, baby boomers

Click to More Senior News on the Front Page





Published by New Tech Media -

Other New Tech Media sites include,,,, etc.