[NavBar.htm]

Senior Journal: Today's News and Information for Senior Citizens & Baby Boomers

More Senior Citizen News and Information Than Any Other Source - SeniorJournal.com

Go to more on Health & Medicine or More Senior News from SeniorJournal.com on the Front Page

   

E-mail this page to a friend!

Health & Medicine for Senior Citizens

Avodart Not Cost Effective Way to Prevent Prostate Cancer in Some Men

For average man, dutasteride provides minimal survival benefits, reduction on treatment-related complications does not offset the high costs

Feb. 8, 2011 The popular drug Avodart (dutasteride) may not be a cost-effective way to prevent prostate cancer in men who are at elevated risk of developing the disease, according to findings by a UT Southwestern Medical Center researcher. Prior research has shown the drug lowered the risk of prostate cancer over a four-year period by 22.8 percent, but questions have remained about its cost-effectiveness.

In a study available in the January issue of Cancer Prevention Research, investigators found that the medication, at an annual cost of $1,400, is impractical when compared to the marginal impact on survival and quality of life in at-risk groups. The drug is primarily for the treatment of enlarged prostates but also is widely prescribed for chemoprevention.

 

Related Archive Stories

 
 

Study Finds Way to ID Aggressive Prostate Cancers; Save Men from Aggressive Therapy

Many prostate cancer patients treated unnecessarily; vast majority would not become life-threatening, even if left untreated

Feb. 3, 2011


 
 

Read the latest news
> Health & Medicine
>
Today's Headlines

 

"Because prostate cancer is the most common cancer in men, the implications of this data are significant since there could be millions of men who would be eligible for anti-cancer drugs," said Dr. Yair Lotan, associate professor of urology at UT Southwestern.

"Prior to instituting a chemoprevention strategy to a large population, the utility and cost need to be well understood. Whether a medication improves survival, how it affects quality of life, and what its financial implications will be are all critical issues.

Because Avodart typically is prescribed for the lifetime of the patient, and therefore taken daily for decades, the cost issue is particularly relevant."

The current study analyzed the lifetime health-related costs of the drug in patients at greater risk of developing prostate cancer and compared them to other factors, such as quality and length of life.

Dr. Lotan and his colleague, Dr. Robert Svatek of UT Health Science Center at San Antonio, used a Markov probability model to compare the lifetime cost of taking Avodart with no therapy. They used data from a previous trial and studies that evaluated outcomes of patients with prostate cancer, including treatment-related complications to create the model.

The primary outcome was measured in quality-adjusted life years (QALY), which takes into account both quality and quantity of life.

"The study found that Avodart was not cost-effective for chemoprevention unless and until a strategy is developed for targeting very high-risk patients and the cost of the drug decreases," said Dr. Lotan.

"For the average man, the drug provides minimal survival benefits, and the reduction on treatment-related complications does not compensate for the high costs of every man taking the drug for many years."

Why is this medication prescribed?

Dutasteride is used to treat an enlarged prostate (benign prostatic hyperplasia, or BPH). Dutasteride is in a class of medications called 5-alpha reductase inhibitors. It works by blocking the production of a natural substance that enlarges the prostate. This shrinks the prostate, relieves symptoms of BPH, such as frequent and difficult urination, and decreases the chance that surgery will be needed to treat this condition. Learn more at PubMed Health

>> Avodart Web Site

 

> Medical Malpractice,

> Nursing Home Abuse,

> Personal Injury

Our Experienced Lawyers Can Help

Beth Janicek, Board Certified Personal Injury Attorney"We win because we care, we prepare and we have no fear," Beth Janicek, board certified personal injury attorney

 

Free Consultation on your case.

Call Now Toll Free

1-877-795-3425

or Send Email

More at our Website

 

 

Search for more about this topic on SeniorJournal.com

Google Web SeniorJournal.com

Keep up with the latest news for senior citizens, baby boomers

 

Click to More Senior News on the Front Page

Copyright: SeniorJournal.com

    

 

Published by New Tech Media - www.NewTechMedia.com

Other New Tech Media sites include CaroleSutherland.com, BethJanicek.com, SASeniors.com, DrugDanger.com, etc.