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Hospital stays for MRSA staph infections 1993 though 2005

Senior Citizen Health & Medicine

MRSA Staph Infection Hits Senior Citizens Hardest, Hospitalizations Up 10 Fold Since 1995

Superbug hospitalizations in 2005 were 3 times over 2000, up 30% in just one year

   
 

Rates of hospitalization with MRSA infection per 100,000 population, by age group, 2004

Source: AHRQ, Center for Delivery, Organization, and Markets, Healthcare Cost and Utilization Project, Nationwide Inpatient Sample, 2004

 

Nov. 7, 2007 - It’s commonly just referred to as “MRSA” or sometimes as the “superbug.” The terrible reality is that it is an infectious disease with the ability to fight off attempts to kill it with antibiotics and it is crawling across the America, escaping from its normal habitat in healthcare facilities and striking thousands of senior citizens – three times as many as any other age group.

 

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Oct. 16, 2007 - Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) appears to be more prevalent than previously believed, affecting certain populations disproportionately – senior citizens in particular - and is being found more often outside of health care settings, according to a study in the October 17 issue of Journal of the American Medical Association. Methicillin is used to treat penicillin-resistant infections.

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There were 368,000 hospitalizations in 2005 for MRSA, which was ten times larger than 1995 and even triple the number in just 2000. It was a 30 percent jump over 2004.

The highest rate of MRSA hospitalization was among the elderly - 360.8 of every 100,000 hospital stays were for MRSA treatment.

This was more than three times higher than for any other age group:
  >19.2 for 1- to 17-year-olds,
  >58.1 for 18- to 44-year-olds, and
  > 111.5 for 45- to 64-year-olds per 100,000.

 
 

These are just some of the facts released in a statistical report, Infections with Methicillin-Resistant Staphylococcus Aureus (MRSA) in U.S. Hospitals, 1993–2005, from Healthcare Cost and Utilization Project of the Agency for Healthcare Research and Quality. Authors are Anne Elixhauser, Ph.D. and Claudia Steiner, M.D., M.P.H.

Infections with methicillin-resistant Staphylococcus aureus (MRSA) are resistant to the antibiotics normally used to treat them (beta-lactam antibiotics, including methicillin, oxacillin, amoxicillin, and penicillin), according to the brief.

“Although Staphylococcus is a common bacterium that resides on skin and in nasal passages, it can cause infections if it enters the body through a cut in the skin, and these infections can be serious.”

MRSA infections can occur among hospitalized patients who under-go surgery or who have suppressed immunity; however, they also increasingly occur among non-hospitalized patients who are other-wise healthy, the report says.

The authors say that from current evidence it is not possible to determine whether these infections originated in the hospital or were community acquired.

Key Findings

  ● On average, hospital stays for MRSA infections cost $14,000, compared with $7,600 for all other stays, and the length of hospitalization was more than double - 10.0 days for MRSA infections versus 4.6 days for all other stays.

  ● MRSA hospitalizations were more likely to begin in the emergency department, to be trans-fers from another hospital, or transfers from long-term care settings. The in-hospital death rate for MRSA stays was 4.7 percent compared with 2.1 percent for non-MRSA stays.

  ● The most common conditions associated with MRSA are skin infections (18.9 percent of all MRSA cases), pneumonia (9.0 percent), complications of medical care (about 16 percent), and septicemia (7.3 percent).

  ● Hospital stays for MRSA infections were highest in the South where there were 113.2 MRSA hospitalizations per 100,000 population. In the West, there were 95.9 MRSA stays, and in the Midwest and Northeast, there were about 89 MRSA stays per 100,000.

  ● Figure 1 shows the growth in MRSA infections over the 13 years from 1993 to 2005. In 2005, there were about 368,600 cases of MRSA infection in U.S. hospitals, a figure that increased by 30 percent after 2004, more than tripled after 2000, and increased nearly tenfold after 1995. In 1993, there were fewer than 2,000 MRSA infections recorded in U.S. hospitals.

Characteristics of patients with MRSA infections

  ● Overall, 44.0 percent of all hospital inpatients with MRSA in 2004 were over the age of 65, 27.6 percent were 45 to 64 years old, and 22.2 percent were age 18 to 44.

  ● Compared with patients without MRSA infections, a significantly larger proportion of patients in the hospital with MRSA infections tended to be 45 years and older.

  ● With respect to gender, only 47.3 percent of MRSA patients were female compared with 59.0 percent of non-MRSA patients.

  ● Parallel to the age distribution, 45.6 percent of all MRSA hospitalizations were covered by Medicare compared with 32.9 percent of hospital stays during which MRSA was not recorded.

  ● A significantly smaller proportion of MRSA patients were covered by private insurance (20.4 percent) compared with non-MRSA patients (34.5 percent).

  ● There was no difference in MRSA infection rates for patients covered by Medicaid and for the uninsured.

  ● MRSA hospitalizations were more likely to begin in the emergency department (56.8 percent versus 43.0 percent for non-MRSA stays), to be transfers from another hospital (5.9 percent versus 3.5 percent for non-MRSA stays), or transfers from long-term care settings (4.4 percent versus 1.5 percent for non-MRSA stays).

  ● The in-hospital death rate for MRSA hospitalizations was more than double that for non-MRSA-stays (4.7 percent versus 2.1 percent).

Resource use for MRSA hospital stays

  ● MRSA hospitalizations cost nearly double that for non-MRSA stays - $14,000 for MRSA stays compared with $7,600 for non-MRSA stays.

  ● The average length of stay in the hospital for a patient with MRSA infection was more than double that for non-MRSA stays - 10.0 days versus 4.6 days.

Population rates of MRSA hospitalization

  ● The rate of MRSA infection was highest in the South where there were 113.2 MRSA-related hospital stays per 100,000 population.

  ● The next highest rate was in the West with 95.9 stays per 100,000 population.

  ● The Northeast and the Midwest had comparable rates of about 89 stays per 100,000 population.

  ● The rate of MRSA infection was higher for males than for females - 106.6 stays per 100,000 population for males compared with 92.2 for females.

  ● The highest rate of MRSA hospitalization was for those 65 years and older with 360.8 stays per 100,000. Infants less than one year of age were the next highest group with 114.7 MRSA stays per 100,000 population. This group was followed closely by 45 to 64 year olds who had 111.5 MRSA stays per 100,000 population.

  ● Patients in the 1 to 17 year age group had the lowest rate of MRSA infections.

  ● Parallel to the findings by age, there were 331.6 stays per 100,000 for patients covered by Medicare.

  ● Patients covered by Medicaid had 184.1 stays per 100,000, and the uninsured had 43.2 stays per 100,000.

  ● All these rates were higher than the rate for the privately insured.

Most common principal diagnoses associated with MRSA infections

MRSA infection can only appear as a secondary diagnosis; the principal diagnosis provides information on the main reason for admission to the hospital.

  ● Five of the top 10 principal conditions were related to infections - skin and subcutaneous infections and pneumonia (the two most common conditions), septicemia, infective arthritis and osteomyelitis, and urinary tract infections.

  ● The third and fourth most common conditions represented complications of medical care (about 16 percent of MRSA cases).

  ● Complications from diabetes ranked seventh (3.3 percent of MRSA cases).

  ● Also ranked in the top 10 were respiratory failure (an indication of the seriousness of this condition) and chronic ulcer of the skin. condition) and chronic ulcer of the skin. All of these conditions were significantly more common among MRSA patients than among patients with no MRSA infection.

  ● All of these conditions were significantly more common among MRSA patients than among patients with no MRSA infection.

Most common procedures associated with MRSA infections

  ● The top two procedures associated with MRSA infections are related to surgical treatment of skin infection - incision/drainage and debridement of skin. These procedures were performed in about 13 percent of cases, many times more frequent than among non-MRSA patients.

  ● A third procedure that is likely related to surgical care of infection was partial excision of the bone, accounting for 1.4 percent of cases.

  ● Blood transfusions, respiratory intubation, hemodialysis, and enteral and parenteral nutrition all signal severe illness and were performed more frequently for MRSA patients. Several diagnostic studies were relatively common and more prevalent among MRSA patients.

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