Senior Journal: Today's News and Information for Senior Citizens & Baby Boomers

More Senior Citizen News and Information Than Any Other Source - SeniorJournal.com

Go to more on Senior Citizen Alerts or More Senior News on the Front Page

 
 

E-mail this page to a friend!

 

Senior Citizen Alerts

Mayo Clinic Links Common Blood Pressure Drug to Severe GI Problems

Patients in clinical trial taking Olmesartan (Brenicar) had symptoms of celiac disease - video discussion below news story

June 21, 2012 - Mayo Clinic researchers have discovered an association between a commonly prescribed blood pressure drug, Olmesartan (brand name: Benicar), and severe gastrointestinal issues such as nausea, vomiting, diarrhea, weight loss and electrolyte abnormalities - symptoms common among those who have celiac disease. The findings are published online today in the medical journal Mayo Clinic Proceedings.

Mayo Clinic physicians treated 22 patients with symptoms similar to celiac disease, including intestinal inflammation and abnormalities from 2008-2011. Patients came from 17 states, and some had been diagnosed with celiac disease.

 

Related Stories

 
 

Task Force Wants Lung Cancer Screening Guidelines Pushed to Age 79

Guidelines expand recommended use of low-dose computed tomography - June 21, 2012

Relief from Pain of Shingles May Soon by On Way with Horizant Approval by FDA

GSK and XenoPort get approval for valuable drug to treat postherpetic neuralgia but relief for senior victims may be delayed by contract dispute, says Reuters - June 8, 2012

FDA Issues Alert on Reumofan Plus. Dietary Supplement Used for Pain Relief

Health officials in Mexico order recall based on potentially harmful pharmaceutical ingredients - June 8, 2012

High Risk of Major Bleeding from Low-Dose Aspirin Found by New Study

Study looked at those with and without diabetes in large study; aspirin appears to not increase risk for diabetics but non diabetics - June 5, 2012


Read more Senior Citizen Alerts

 

They had chronic diarrhea and weight loss; the median weight loss was 39 pounds, and one patient lost 125 pounds. Fourteen of the 22 were hospitalized because of the severity of their symptoms. When given a blood test, however, these patients didn't come back with results typical of celiac disease. They also didn't respond to treatments such as gluten-free diets.

After examining their medications, Mayo Clinic gastroenterologist Joseph Murray, M.D., pulled several of the patients off Olmesartan. Their symptoms dramatically improved. Eventually, all 22 were taken off the drug, and all showed improvement. Eighteen of the 22 patients had intestinal biopsies after stopping the medication and showed improvement.

"We thought these cases were celiac disease initially because their biopsies showed features very like celiac disease, such as inflammation," says Dr. Murray, the lead author. "What made them different was they didn't have the antibodies in their blood that are typical for celiac disease."

(Watch video of Dr. Murray below news story)

Olmesartan - prescribed for the treatment of hypertension, or high blood pressure - works by blocking substances that tighten blood vessels, allowing blood to flow more smoothly and the heart to pump more efficiently, according to the U.S. National Library on Medicine.

"Olmesartan is also sometimes used to treat congestive heart failure (condition in which the heart is unable to pump enough blood to the rest of the body) and diabetic nephropathy (kidney disease in people with diabetes and high blood pressure)," the NLM report says.

"It's really an awareness issue. We want doctors to be aware of this issue, so if they see a patient who is having this type of syndrome -- they think about medications as a possible association," Dr. Murray says. "We've reported an association. What needs to be known next is the science to understand why there is such an association."

The investigators were supported in part by the National Institutes of Health, the American College of Gastroenterology Junior Faculty Development Award, the Swedish Society of Medicine, the Swedish Research Council and the Fulbright Commission.

About Mayo Clinic

Mayo Clinic is a nonprofit worldwide leader in medical care, research and education for people from all walks of life. For more information, visit http://www.mayoclinic.org/about/ and http://www.mayoclinic.org/news/.

>> FDA Safety Alert on Olmesartan in 2011

>> More on Olmesartan at National Library of Medcine

>> Choosing medicine for high blood pressure - National Library of Medicine

Nursing Home Abuse,
Medical Malpractice -
Experienced Legal Help

 Beth Janicek, Board Certified Personal Injury Attorney Janicek Law attorneys are working every day to help senior citizens and others harmed by failure of care in nursing homes and the healthcare system.

If you or a loved one have suffered due to the neglect or inadequate care of others, call us today. We offer the skill and knowledge gained in more than twenty years of success.

Free Consultation - Call toll free 1-877-795-3425 or Email

 

Search for more about this topic on SeniorJournal.com

Google Web SeniorJournal.com

Keep up with the latest news for senior citizens, baby boomers

Click to More Senior News on the Front Page

Copyright: SeniorJournal.com

    

Published by New Tech Media - www.NewTechMedia.com

Other New Tech Media sites include CaroleSutherland.com, BethJanicek.com, SASeniors.com, DrugDanger.com, etc.